Are you struggling to build the perfect team in Anime Guardians? With so many units and artifacts to choose from, it’s easy to get overwhelmed. Our comprehensive Anime Guardians Tier List breaks down exactly which units dominate the current meta, which artifacts you should prioritize, and how to build unstoppable team compositions that will carry you through any challenge.
Key Takeaways
- Meta Tier Units like Subaru (Greed) and Reinhard dominate all game modes with insane damage output
- Secret Units offer the highest power potential but require significant grinding to obtain
- Curse Book and Antique Earring artifacts provide the biggest damage boosts for most units
- Team composition matters more than individual unit strength – balance DPS, support, and utility
- Update 21 heavily favors curse, bleed, and burn-based damage types
Understanding the Tier System
Before diving into specific units, it’s important to understand how our Anime Guardians Tier List works. We rank units based on their overall performance across all game modes, including story progression, infinite modes, and boss battles. Units are evaluated on damage output, survivability, utility, and how well they scale with artifacts.
Tier Meanings:
- Meta: These units completely dominate the game and are essential for competitive play
- SSS: Extremely powerful units with minimal weaknesses
- SS: Strong and reliable choices for most content
- S: Good units that perform well with proper investment
- A: Decent units that work in specific situations
- B: Average units that can be replaced easily
- C: Below average units that should be replaced quickly
- D: Units that aren’t worth using at all
Meta Tier Units – The Absolute Best
These units define the current Anime Guardians meta and should be your top priority if you want to dominate every game mode. Getting even one of these units can dramatically improve your progression.
Subaru (Greed) – Secret Unit
Subaru (Greed) stands at the top of our Anime Guardians Tier List for good reason. This unit offers insane DPS scaling that grows exponentially as battles progress. His unique ability to synergize with curse-based artifacts makes him unstoppable in extended fights. When paired with the Curse Book artifact, Subaru can achieve damage numbers that other units can only dream of.
Why he’s Meta:
- Massive damage scaling that increases over time
- Perfect synergy with curse artifacts
- Excellent boss killer with consistent damage output
- Works well in both solo and team compositions
Reinhard (Strongest Human) – Limited Unit
Reinhard brings raw power and consistency to any team. As a Limited unit, he’s harder to obtain but worth every effort. His ability to deliver massive damage without requiring complex setups makes him perfect for players who want straightforward power.
Strengths:
- Consistent high damage across all fight durations
- Great survivability with built-in defensive abilities
- Excellent for both early progression and endgame content
- Synergizes well with most support units
Regulus (Alpha Leonis) – Secret Unit
Regulus excels at taking down tough bosses with his specialized boss damage abilities. His survivability is unmatched among DPS units, allowing him to stay in fights longer and deal more damage overall.
Key Features:
- Massive boss damage multiplier
- High survivability with defensive abilities
- Scales incredibly well with investment
- Essential for raid and boss content
SSS Tier Units – Elite Powerhouses
Just below the Meta tier, these SSS units offer incredible performance and should be your next priority if you can’t obtain Meta units.
Typhon (Witch of Pride) – Secret Unit
Typhon brings devastating area-of-effect damage and powerful debuffs to the battlefield. Her ability to weaken enemies while dealing massive damage makes her invaluable in team compositions.
Daphne (Witch of Gluttony) – Secret Unit
Daphne specializes in damage-over-time effects that can melt through even the toughest enemies. Her poison and burn abilities stack quickly, making her perfect for extended battles.
Carmilla (Witch of Lust) – Secret Unit
Carmilla combines curse and bleed mechanics for devastating damage output. She’s particularly effective against bosses and high-health enemies where her damage-over-time effects can shine.
Best Artifacts in Anime Guardians
Artifacts can make or break your units in Anime Guardians. The right artifact combination can elevate even average units to god-tier performance.
Top Tier Artifacts
| Artifact | Effect | Best For |
| Curse Book | 2× damage boost, reduced cooldown | Curse-based units |
| Antique Earring | +100% active skill damage | Units with strong active skills |
| Netherbane Flail | Massive burn damage boost | Fire/burn units |
| Greenbone Greatsword | Bonus boss damage and cooldown | Boss-focused teams |
| Toxic Greatsword | Poison stacking on hit | Poison/DoT units |
Artifact Strategy Tips
- Match artifacts to unit abilities – Don’t just use the highest tier artifact; choose one that complements your unit’s strengths
- Consider cooldown reduction – Many top artifacts reduce cooldowns, allowing for more frequent ability usage
- Build around damage types – Focus on either curse, bleed, or burn damage for maximum effectiveness
- Balance offense and defense – Sometimes a slightly weaker artifact with defensive benefits can be better for progression
Anime Guardians Team Compositions
Building the right team is crucial for success in Anime Guardians. Here are some proven team compositions that work well in the current meta.
Late Game DPS Team
- Main DPS: Subaru (Greed) or Reinhard
- Secondary DPS: Regulus (Alpha Leonis)
- Support: Curse applicator unit
- Utility: Cooldown reduction unit
- Artifact Focus: Curse Book on main DPS, support artifacts on utility units
This team composition maximizes damage output while maintaining survivability through curse effects and cooldown management.
Farming Team
- Main DPS: High AoE unit like Typhon
- Secondary DPS: Farm-specialized unit
- Support: Cooldown-based support unit
- Artifact Focus: Area damage and cooldown reduction artifacts
Perfect for clearing waves quickly and efficiently farming resources.
Beginner-Friendly Team
- Main DPS: Any S tier unit you can obtain
- Support: Healing or defensive unit
- Utility: Status effect unit
- Artifact Focus: General damage boost artifacts
This balanced composition helps new players progress through early content without requiring rare units.
How to Get Better Units in Anime Guardians
Getting top-tier units requires strategy and patience. Here are the best methods to improve your roster:
Summoning Strategy
- Save currency for limited banners – Limited units offer the best value
- Focus on quality over quantity – One SSS unit is better than five B tier units
- Check banner rates – Some banners have better rates for specific unit types
Alternative Methods
- Tower challenges – Clear tower floors for guaranteed unit rewards
- Leaderboard rewards – Compete in events for exclusive units
- Trading – Trade with other players for units you need
- Evolution – Evolve existing units to unlock their full potential
Common Mistakes to Avoid
Many players make these mistakes when building their teams in Anime Guardians:
- Ignoring unit synergy – Don’t just stack the highest tier units; consider how they work together
- Wrong artifact choices – Using top-tier artifacts on units that don’t benefit from them
- Neglecting support units – DPS isn’t everything; support units can dramatically increase team effectiveness
- Spreading resources too thin – Focus on building 3-4 units rather than trying to upgrade everything
- Not adapting to updates – The meta changes with each update; stay flexible with your team composition
Frequently Asked Questions
How do I get secret units in Anime Guardians?
Secret units are the hardest to obtain but offer the highest power potential. You can get them through special event banners, tower completion rewards, and occasionally from limited-time summoning events. Save your gems for these opportunities and check the official Discord for announcements about upcoming secret unit releases.
What’s the best artifact for beginners?
For beginners, the Antique Earring is often the best choice since it provides a straightforward 100% damage boost to active skills without requiring complex setup. As you progress, you can transition to more specialized artifacts like Curse Book or Netherbane Flail based on your units’ abilities.
How often does the Anime Guardians meta change?
The meta typically shifts with major updates, which usually happen every 2-3 weeks. Balance patches can change unit rankings overnight, so it’s important to stay updated through the official Discord and community resources. However, Meta tier units usually remain strong even through balance changes.
Should I evolve my units immediately?
Not necessarily. While evolving units increases their power, it also requires significant resources. Focus on evolving your core team first (3-4 units) rather than spreading evolution materials across many units. A fully evolved SSS unit is better than multiple partially evolved A tier units.
What’s the best team composition for infinite mode?
Infinite mode teams need sustained damage and survivability. The best composition typically includes: one main DPS with curse/bleed effects, one secondary DPS for cleanup, one support unit for healing/buffs, and one utility unit for crowd control. Artifacts should focus on damage-over-time effects and cooldown reduction.
Conclusion
Mastering Anime Guardians requires understanding both individual unit strength and team composition dynamics. This Anime Guardians Tier List gives you the foundation to build powerful teams, but remember that the best players adapt their strategies based on available units and current meta trends.
Focus on obtaining at least one Meta or SSS tier unit, pair it with complementary artifacts, and build a balanced team around it. Don’t be afraid to experiment with different combinations – sometimes unexpected unit pairings can create devastating results.
Keep checking back for updates as the meta evolves with new releases and balance changes. The world of Anime Guardians is always changing, and staying informed is key to maintaining your competitive edge.
Ready to dominate the battlefield? Start building your dream team today and climb those leaderboards!
